TB-500 — Thymosin Beta-4 Fragment Peptide
TB-500 is a synthetic peptide representing the active region of Thymosin Beta-4 (Tβ4), a 43-amino acid protein naturally produced by the thymus gland. As the primary intracellular G-actin sequestering peptide, Thymosin Beta-4 plays a fundamental role in cell motility, migration, and tissue repair — making TB-500 an essential research tool for regenerative biology studies.
Mechanism of Action
TB-500 promotes cellular responses through actin polymerization regulation, which is critical for cell migration and proliferation during wound repair. The peptide upregulates cell-building proteins such as actin, facilitates new blood vessel formation through angiogenesis, and reduces pro-inflammatory cytokine expression. Its low molecular weight allows efficient distribution through tissues with high bioavailability at injury sites.
Research Applications
- Tissue repair and wound healing mechanisms
- Actin polymerization and cytoskeletal organization
- Angiogenesis and new blood vessel formation
- Anti-inflammatory pathway modulation
- Cardiac tissue remodeling studies
- Stem cell differentiation and migration research
Product Specifications
- Quantity: 5/10mg per vial
- Purity: ≥98% (HPLC verified)
- Form: Lyophilized powder
- Storage: Refrigerate after reconstitution
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